Female human livers exhibit higher carboxylesterase-1 (CES1) protein abundance and increased in vitro activation rates for several CES1 substrates, including oseltamivir (conversion to oseltamivir carboxylate) and dabigatran etexilate (conversion to dabigatran) (Shi et al
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Spleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome-mediated IL-1 secretion via c-Jun N-terminal kinase activation and cell apoptosis during diabetic nephropathy
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The therapeutic potential of (-)-Vestitol and Salviolone as novel candidates for AD treatment is underscored by their synergistic effects, attributed to their comprehensive regulation of AD-associated pathways and genes
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