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42 The mechanism by which tobacco products (either smoking or smokeless) have elevated the risk of renal disorders may be through enhancing the synthesis of free radicals which may result in alterations of glomerular function leading to elevated levels of urea and creatinine in tobacco chewers and smokers

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[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Shihadeh A, Schubert J, Klaiany J, El Sabban M, Luch A, Saliba NA