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A first mechanism is the direct interaction with the reducing thiolate, leading to irreversible inactivation of the active site, as described for the inactivation of GSTs (Scheme 9)

Batch: GF-AOD5-B241 Assay Content: 4.86 mg Purity: greater than 99.8 percent Identification by Spectrum: 986 Identification by Retention Time: 0.996 Molecular Ion Mass Identification: 1815 Da Bacterial Endotoxins: 0.009 EU/mg Total Aerobic Microbial Count: Not detected Total Yeast and Mold Count: Not detected Research Applications In controlled laboratory environments, AOD-9604 may be utilised in experimental models designed to investigate peptide signalling systems and molecular communication pathways

2020 DOI: 10.1002/brb3.1726 PMID: 32558293 Read on PubMed 8 peer-reviewed references listed

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As a naturally occurring tripeptide complexed with copper (II), GHK-Cu is one of the most extensively studied peptides in published research literature exploring skin biology, gene expression modulation, and extracellular matrix remodelling pathways