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One accelerating factor, for example, is the menopause

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Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects

Sturm and Wells note that "Americans haven't given obesity the same attention as other risks, like smoking, but it is clearly a top health problem and one that is on the rise in all segments of the population

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