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In 2004, the International Agency for Research on Cancer (IARC) judged that there was sufficient evidence in humans that tobacco smoking causes cancers of the lung, larynx, oral cavity and pharynx, paranasal sinuses, oesophagus, stomach, pancreas, liver, kidney, ureter, bladder, uterine cervix and bone marrow (myeloid leukaemia

And a recent study in the UK found nicotine-free vapes can contain as much nicotine as a full-strength e-cig after examining more than 50 brands sold in the country

Department of Health and Human Services, Centers for Disease Control and Prevention NCfCDPaHP, Office on Smoking and Health, eds

It also thickens the blood, so the heart has to work harder to pump the blood around the body

Ronald Reagan (1911 2004), 40th President of the United States served two terms in office: 1981 - 1989

Next up is Players from Imperial Tobacco, which moves up one place in the rankings from last year with sales of 734m, which was 42.8% up the fastest growth rate of any of the top 10 brands