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Draw a 2D net with fold lines and glue tabs

As tolerance builds, the brains reduced sensitivity to nicotine requires higher doses to elicit the same response

These chemicals and oxidative substances are toxic to cells, and can: Permanently damage tissues Cause cells to become inflamed Cause cell mutations Switch on carcinogenic genes Impair immune function Stimulate the development of autoimmunity How are Cigarettes Related to Type 2 Diabetes

A recent study in the International Journal of Environmental Research and Public Health shows 9.7 billion cigarette butts are tossed in the US each year, with 4 billion of those ending up in waterways.

Its not just tired but uninspired

The mucus produced by smokers is often thicker and more difficult to expel