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Study A, B and C [see Clinical Studies (14.1)]

In addition to being a serious comorbidity, obstructive sleep apnea syndrome (OSAS) exerts a negative influence on weight loss capacity by impairing muscle energy metabolism, reducing exercise capacity, and altering ghrelin levels that regulate hunger (94)

Available online: 7.Poirier P., Giles T.D., Bray G.A., Hong Y., Stern J.S., Pi-Sunyer F.X., Eckel R.H., American Heart Association

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