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The construction method is die-cut cardstock a process that was standard for high-volume point-of-sale production in this era, but that required precise registration and clean cutting to achieve the dimensional, sculptural effect you see here

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Compared with nonsmokers, moderate to heavy smokers ( 10 cigarettes/day) had baseline levels (e.g., early follicular phase) of both steroid metabolites that were 2535% higher, and heavy smokers ( 20 cigarettes/day) had lower luteal-phase progesterone metabolite levels