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Nicotine significantly reduced IL-8, IL-6 and VEGF levels in keratinocytes and endothelial cells co-cultured with the serum of Bechet patients (Kalayciyan et al., 2007), indicating that nicotine has therapeutic potential in reducing systemic vascular inflammation

10.1152/ajplung.00330.2013 Summary Keywords epigenome and exposome, comorbidities, oxidative stress, hyperinsulinemia and insulin resistance, subclinical inflammation, microbiome, psoriasis, multiple sclerosis Citation Kopp W (2022) Pathogenesis of (smoking-related) non-communicable diseasesEvidence for a common underlying pathophysiological pattern