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The pharmacologic effect of nicotine at BBB is partly due to stimulation of nAchRs in brain endothelial cells that express -3, -5, -7, -2, and -5 of its subtypes (Moccia et al., 2004)

A persons risk of alcohol-related cancers is influenced by that persons genes, specifically the genes that encode enzymes involved in metabolizing (breaking down) alcohol (27)

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