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Drug discrimination procedures are well-established in both human and preclinical studies for assessing subjective/interoceptive effects (Grant and Bennett 2003

Glossitis (inflamed tongue) usually resolves within two to three weeks, and patients report reduced oral discomfort

If constipation becomes persistent or chronic, a healthcare provider should evaluate the situation and discuss longer-term management options

Even if a substance is not included on the ingredient list, the supplement could have been contaminated during the manufacturing process, supply chain, or by way of raw material which could lead to inadvertent doping

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