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Nicotine blocks lymphocyte proliferation and differentiation, including suppressing antibody-forming cells by inhibiting antigen-mediated signaling in T-cells and ribonucleotide reductase

Systemic effects Beyond direct hepatic impact, smoking exerts systemic effects that indirectly contribute to liver disease progression

It has the same addictive nicotine of cigarettes, and thousands of toxic chemicals, many known to be carcinogenic

PMID 16880445

A study found that the risk of liver cancer among people who quit smoking was similar to that of non-smokers, while current smokers had a significantly higher risk

Follow me on Twitter @RobShmerling About the Author Robert H