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Men and older adults are more affected by high triglyceride levels

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Important safety considerations when using these supplements together include: Drug interactions : Berberine may potentially interact with numerous medications, including antidiabetic drugs (increasing hypoglycaemia risk), anticoagulants, and medications metabolised by CYP450 enzymes (such as ciclosporin and certain statins)

References: Desai, D

If thats your situation, ask your healthcare provider for help, including mental health support