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Mendelian randomisation (MR) analysis In the present study, a modified Mendelian randomisation approach was performed to investigate a potential causal relationship 36,65 , in which non-pleiotropic polygenic risk scores (i.e., the valid-PRS) were established as instrument variables of randomised experiments for potential causal inference

Nearly half of these deaths will be attributable to cancers caused by potentially modifiable risk factors (46)

Upon direct request by other researchers and in mutual agreements regarding data protection, anonymized data could be made available (e.g., MRI data after defacing)

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So stay vigilant for any worsened hotness, swelling, itching, or irritation if opting to smoke