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Only a minority of compounds were present in THS aerosol at higher concentrations than those measured in the smoke of the 3R4F reference cigarette

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Therefore, metabolomics has been widely applied in various fields, such as drug toxicity, disease diagnosis, and pharmacodynamic study [40,41,42]

While not universally effective for everyone, many users find e-cigarettes helpful in reducing tobacco dependence.

The higher nicotine content helps replicate the sensation of smoking a traditional cigarette, making the transition smoother and reducing the likelihood of returning to smoking

Various government programs and campaigns, like the Campaign for Tobacco-Free Kids, aim to support individuals in their journey to quit smoking