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Compared with placebo, the likelihood of quitting smoking was roughly doubled with NRT (1.84, 95% CI 1.711.99) and bupropion (1.82, 1.602.06) and was improved further with varenicline (2.88, 2.403.47) (Cahill et al., 2013)

It is not clear to us why country-specific differences were observed for both interest in quitting and quit attempts, even after adjustment for sociodemographic differences

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These changes in the blood lining over time, lead to accumulation of plaque and narrowing of the blood vessels