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Their key role involves reducing dietary nitrate (from saliva) to nitrite, the first step in the entero-salivary nitrate-nitrite-nitric oxide pathway, which has crucial systemic vascular implications (e.g., blood pressure regulation) (Rosier et al., 2024
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The CLOZUK study conducted GWAS analysis through GCTA (Genome-wide Complex Trait Analysis) software (Table 1 summarizes the basic features of the GWAS samples
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