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Four nested logistic regression models were constructed in these groups, each building upon the previous one by adding sequentially explanatory variables: sex, age, and race/ethnicity in Model 1, plus citizenship in Model 2, plus BMI and PIR in Model 3, plus education level in Model 4

Many smokers who switch from regular cigarettes to Esse Change appreciate the stylish slim design, smoother draw, and the freedom to choose when and how to activate their flavor

N Engl J Med 2011

"Prevention is the best strategy, and youth are especially vulnerable to nicotine addiction," Irvin said in the release