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doi: 10.1016/j.anai.2020.05.028 199 YanFLiFLiuJYeSZhangYJiaJet al

While we certainly do not advocate smoking as a means of reducing the risk of gout, further studies are needed to verify this finding and elucidate the suppressive effects of nicotine on the pathophysiology of gout.

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Unfortunately, quitting smoking can be challenging due to uncomfortable physical withdrawal symptoms, such as nicotine cravings, irritability, difficulty concentrating, depression, insomnia, and increased appetite