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In men, the population-attributable risk (PAR) was 52.2% for current smokers and 14.8% for ex-smokers

Given that IL-1RA competes with IL-1 for binding to the IL-1 receptor and prevents IL-1-induced pro-inflammatory signalling we wondered if the increased production of IL-1RA in smokers was associated with high IL-1 levels

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Our data support the growing body of research that suggests illicit markets for menthol cigarettes thrive following state-imposed bans on those products

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