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Notably, heterogeneity tests between different dose groups (p=0.049) further validate the gradient effect: the consistency of effects in the high-dose group (20 cigarettes/day, I 2 =0.0%) suggests a more direct toxic mechanism, such as inhibition of placental angiogenesis

Shaw et al., Management of Fatigue, A Physiological Approach, American Journal of Medical Science, 1962;243:98109, 75869

When they try to quit, they experience both mental and physical discomfort, symptoms of nicotine withdrawal

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While the "magic-eye" indicators can be helpful, they only reflect the condition of one cell out of six, so they should not be solely relied upon for battery status

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