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Abstract Introduction: Abuse or misuse of tobacco, e-cigarettes, or antidepressants may have serious clinical consequences during adolescence, a sensitive period during brain development when the distinct neurobiology of adolescent serotonin (5-HT) and dopamine (DA) systems create unique behavioral vulnerabilities to drugs of abuse

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Reduced immunity and frequent infections Passive smoking is equally dangerous, especially for children and pregnant women, increasing the risk of asthma, low birth weight, and respiratory illnesses

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