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Recent research demonstrates that nicotine exerts much more anti- than pro-inflammatory effects [6] and a recent review of animal literature in HIV and smoking concluded that preclinical studies using nicotine show mild cognitive enhancement, neuroprotective, and possibly anti-inflammatory effects [26]

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Pritchard et al., 2016)

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In Madrid, outdoor hospitality terraces maintain nicotine concentrations (median=0.42 g/m 3 , IQR: 0.141.59) and PM2.5 (median=10.40 g/m 3 , IQR: 6.7615.47), significantly above urban background levels, especially when areas are fully enclosed or when tobacco odor and multiple lit cigarettes are simultaneously present 10