Mild side effects may include nausea, headache, abdominal discomfort, or temporary skin rashes
Dietary supplements are registered, not "approved" like pharmaceutical drugs
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Biomarkers 11:355369 Tailor P, Raman T, Garganta CL, Njalsson R, Carlsson K, Ristoff E, Carey HB (2005) Recurrent high anion gap metabolic acidosis secondary to 5-oxoproline (pyroglutamic acid)