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The strengths of this study include the large population-based sample, the long follow-up period, the comprehensive approach to investigating genetic risk, the novel investigation of interactions, the careful adjustment for potential confounders, and the use of sensitivity analyses to investigate the robustness of findings
We then measured the levels of IL-1, G-CSF, IL-10, IL-13, IL-17, MIP-1, VEGF, IFN, IL-12, IFN, IL-1RA, TNF, IL-4 and IL-8 using Luminex beads, and IL-6 via mesoscale analysis
