We showed that RSPO2-deficient mice have reduced active -catenin signalling and a decreased mineral deposition rate and osteoblast number, similar to the phenotype observed with the knockout of LRP5/6
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Statistical significance was considered when the P value was equal to or less than 0.05
These findings suggest a potential link between the altered lipid metabolome in aging and the lipid dysregulation observed in AD, highlighting the need to further investigate how age-related lipid changes may contribute to AD pathology
DOI: Published: Publisher Name: Springer, Cham Print ISBN: 978-3-319-28897-0 Online ISBN: 978-3-319-28899-4 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)
We're seeing that GIP receptor activation appears to amplify the metabolic effects in ways we didn't fully anticipate from the preclinical data." , Dr
