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The Zika virus (ZIKV) is a mosquito-borne flavivirus, which causes microencephaly in the newborn and is linked to adult disorders, including encephalitis (Carod-Artal, Human immunodeficiency virus1 causes neurological disorders, including cognitive decline and dementia in 4060% of patients, even with tri-therapy (Anthony et al., 2017) has been linked to neurological disorders (Chaganti et al., Severe acute respiratory syndrome coronavirus-2, the novel coronavirus which emerged in 2019, induces neurological symptoms (encephalitis, GuillainBarre syndrome, epileptic seizures, ischemic stroke, and hemorrhagic stroke) as well as a severe acute respiratory syndrome

To further define the pharmacological profile of PF-06882961, we sought to determine its binding affinity using radioligand binding assays

This behavior is due to the chromatin organization and lamin-A expression (Haase et al., 2016)

The CoQH2/CoQ ratio as a sensor for the mitochondria metabolic status modulates electron flow direction in the mitochondrial respiration as well as the generation of mitochondrial complexes/super-complexes (Guaras et al., 2016)

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