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It is important to take into consideration that though intravenous glutathione is considered to increase its efficacy, it can also pose the risk of overdosing and toxicity (3)
305,306 Despite the biodegradability and biocompatibility of PLL, its in vivo activity remains limited due to its high toxicity, low transfection efficiency, and poor endosomal escape ability
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However, redness may stay, which diminishes gradually