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Unlike the nuclear genome, mitochondrial genomes lack histones, therefore, rather than histone-related modifications, research on mitochondrial gene expression regulation focused on mtDNA methylation and has demonstrated its differences in aging [35, 36] and various diseases including metabolic disorders [37, 38], neurodegeneration [39], and cardiovascular diseases [36, 40]

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Perry states over and over again that he blames no one but himself, though he appears to harbor some resentment toward his parents, whom he feels neglected him for their own careers

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