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Slowing the dose escalation schedule, temporarily returning to a lower dose, or holding at the current dose longer than recommended are options that can improve tolerability while still achieving therapeutic benefits
Exercise provides independent appetite-suppressing effects through PYY and GLP-1 release, partially compensating for the medication gap
202,203,204 Moreover, Akt can activate mTORC1, further promoting cell growth and protein synthesis
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GLP-1s also lower heart disease risk in people who have obesity but not diabetes, according to new research published in the Journal of Diabetes