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Since excise taxes should not serve as tools for general revenue, lawmakers should avoid the temptation to overtax products to raise additional revenue for general spending purposes

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Finally, although POU2F3 or FOXI1 KO severely dysregulated ion transport in ALIs, these cultures robustly retained CFTR activity, as measured by enhanced voltage response to forskolin/IBMX stimulation and CFTR(inh)172 inhibition treatments in KO cultures relative to controls (Fig