Oxidative Stress and Free Radicals Cigarettes generate free radicals that cause oxidative stress, damaging hair follicle cells, disrupting the hair growth cycle and accelerating hair loss
But higher CYP1A1 activity is going to break down estradiol faster, which may be beneficial in estrogen metabolism, depending on your other estrogen-related genes
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Furthermore, plaques obtained from smokers undergoing carotid endarterectomy exhibited increased expression of macrophage-derived MMP-12 compared with nonsmokers