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Although traditionally viewed as a metabolic waste product linked to hypoxic conditions, the significance of lactate in various biological processes is now being reevaluated [2]

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Some of these chemical messengers are free radicals, which are highly reactive species that can either gain or loose electrons, or in proper terminology, take part in oxidation or reduction reactions

Similarly, altitude-correlated EGLN1 variants diminish HIF-2 protein abundance, further associating with reduced hemoglobin levels and inflammatory responses [8,9,10]

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