glp-1 complications receptor agonists and acute diabetes in adults with type 1 diabetes Emergency Presentations of GLP-1 Agonist

doi: 10.1136/bmjopen-2022-061807 108 LiCLuoJJiangMWangK

Longer-term data consistently shows recovery

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Preclinical studies have examined the peptide in models of gastrointestinal injury, epithelial disruption, and anastomosis healing where researchers analyze mucosal architecture, vascular integrity, and epithelial continuity following tissue damage [1]

The mechanism by which bacteria traverse the mucosal barrier remains unclear, with the most convincing studies suggesting that a specific transcytotic process involving specialized cells overlying the domes of intestinal lymphoid aggregates (Peyers patches) termed M-cells, which are characterized by a sparse glycocalyx, short and irregular microvilli and a microfold appearance [16, 17]

Later research used fixed microgram amounts subcutaneously