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Draw inspiration from the original animated film, the 1996 film starring Glenn Close, and the most recent addition of 2021's Cruella , the origin story of the most stylish Disney villain (and one of our favorite Disney Halloween movies)

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Inflammasome assembly leads to caspase 1-dependent release of proinflammatory cytokines IL-1 and IL-18 as well as to gasdermin D (GSDMD)-mediated pyroptotic cell death, facilitating the extracellular release of IL-1 and IL-18 45)