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Circulation 2018;138:861-70

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Step 7: Label and store

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148,149 Literature shows that altered metabolism in neural cells through aberrant insulin signalling could be a reason for the synthesis of A protein and phosphorylated tau, which are two hallmark biochemical abnormalities linked with AD and proper regulation of insulin signalling has been observed to be a crucial approach in neuroprotection and guarding the synapses against noxious A deposition hence improving cognition in animal models of AD

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