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The most frequent genetic mutations in lung cancer occur in the FHIT gene (discussed in the following section), the p53 tumor suppressor gene, and the K- ras protooncogene (27)

66 Tobacco smoke contains volatile and non-volatile N -nitrosamines

Nicotine, found naturally in tobacco plants, is the chemical responsible for the additive nature of cigarettes, cigars, and many e-cigarettes

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Marijuana dependence, also referred to as cannabis use disorder, occurs when someone continues to use marijuana despite experiencing negative consequences

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