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a portion of the NR/NMN is lost in the gut and liver
(n=64,189.) Del Ponte B, Santos IS, Tovo Rodrigues L, et al
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Similarly, in ex situ organ perfusion (ESOP) (60), the absence of the biological role of organs, such as the liver, leads to the inability to scavenge oxygen radicals generated by oxidative stress, thus making such a technique more challenging compared with physiological conditions ( 4.3 Endogenous and exogenous coagulation systems Under normal physiological conditions, coagulation mechanisms include both coagulation and anticoagulation, and the dynamic balance between them plays a key role in maintaining normal blood flow and preventing coagulation (61)