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Despite the global implementation of policies aimed at reducing the use of tobacco, alcohol, and drugs (911), substance use remains among the most pressing public health challenges worldwide

Full COVID-19 GWAS summary-level data is available at FinnGen data are available at lifetime smoking at alcohol drinks per week data at: cannabis use disorder and alcohol use disorder data are available through the Psychiatric Genomics Consortium data portal: and the cannabis use data are available through the International Cannabis Consortium at: Coronary artery disease and obesity summary statistics are available through the Cardiovascular Disease Knowledge Portal: Type 2 Diabetes summary-level data is available Type 2 Diabetes Knowledge Portal: Code availability We used TwoSampleMR and MendelianRandomization R packages to perform Mendelian Randomization analysis

Dimensions: 4107 x 2738 px | 34.8 x 23.2 cm | 13.7 x 9.1 inches | 300dpi Date taken: 7 February 2025 Location: Poland

Potential for dysfunctional eating behaviors The combined effects of nicotine and caffeine on appetite regulation and taste perception may promote dysfunctional eating behaviors in individuals recovering from substance use disorders

This line graph shows the survey years on the horizontal axis and the percentage for past year substance use disorder on the vertical axis