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Additionally, you may see: Social withdrawal Anxiety or paranoia Neglect of responsibilities Increased marijuana tolerance and dependence Legal and financial issues If you notice any of these symptoms in yourself or someone close, it could be a signal that marijuana use is becoming problematic and worth addressing

There can also be respiratory health issues associated with smoking marijuana

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16 Practice Guidelines Given the strong evidence supporting LDL reduction for stroke prevention, the most recent AHA stroke prevention guidelines recommend a target LDL-C of less than 70 mg/ dL in people who have had ischemic stroke or TIA and atherosclerotic disease to reduce the risk of major cardiovascular events (Figure)