glp-1 weight loss comparison Lilly orforglipron oral phase 3 trial GLP-1 medications are marketed to

10.1038/emboj.2013.74 EMBO J

Nauseaa known side effect of GLP-1 therapymay worsen if you fast for extended periods without electrolytes or adequate hydration, so consider a pinch of salt in your water or a sugar-free electrolyte drink during fasting windows if nausea emerges

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The REWIND cardiovascular outcome trial also revealed that dulaglutide administration resulted in inferior ocular outcomes, leading to an increased need for interventions such as photocoagulation, anti-vascular endothelial growth factor (VEGF) therapy, or vitrectomy compared to placebo recipients [38]

attenuates gut dysbiosis and endotoxin leakage against alcoholic liver disease

Low levels of vitamin B12 (vitamin B12 deficiency)