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For example, it is not known whether decreasing fat or increasing fruits and vegetables in the diet helps to decrease the risk of prostate cancer or death from prostate cancer

GLP-1 receptor agonists (semaglutide, liraglutide) are the only peptide-based medicines licensed by the MHRA for weight management in the UK and require a prescription

Available at: (Accessed: 27 February 2026) Semaglutide is highly effective for weight loss, with 2.4 mg once weekly injections, alongside appropriate diet and exercise, reducing mean body weight by 16% after use for 68 weeks

Additionally, the presence of gut microbiota considerably affects the uptake and metabolism of the nutrients

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doi: 10.14348/molcells.2023.0028 120 TakagiY.NakamuraT.NishiyamaA.NozakiK.TanakaT.HashimotoN.et al