avex pharma semaglutide AbbVie gets into obesity with $350M deal for once-weekly shot US FDA says lowest dose

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While incretin-based therapies have been commercially available since 2005, most clinical trials only report short term outcomes

doi: 10.1016/j.cmet.2022.07.013

Manufacturers change raw material sources, adjust synthesis parameters, or experience personnel turnover that can affect batch quality

Peptides like epialin are interesting because they target DNA repair, rather than just working on downstream receptors or vague targets, which is similar to the concept of gene therapy 2m6s

"FDA approves Zepbound for moderate-to-severe obstructive sleep apnea in adults with obesity." December 2024