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It markedly inhibits GPX4 degradation, and lipid peroxidation, and enhances cellular resistance to ferroptosis

Here's everything you need to know about why these two nutrients work so synergistically and how to make the most of them

Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations APX: Ascorbate peroxidase As: Arsenic BSO: Buthionine sulfoximine Cd: Cadmium Cd-GS2: Bisglutathionato cadmium CE: Cation exchange Cr: Chromium Cys: Cysteine Cu: Copper ESI-Q-TOF MS: Electrospray ionization quadrupole time of flight mass spectrometry Fe: Iron GC-MS: Gas chromatography-mass spectrometry GS: Glutathione synthase GSH: Reduced glutathione GSSG: Oxidized glutathione Glu: Glutamate Gly: Glycine HMWC: High molecular weight complex HMT1: Heavy metal transport 1 H NMR: Proton nuclear magnetic resonance Hg: Mercury ICP-MS: Inductively coupled plasma mass spectrometry LC-ESI-MS/MS: Liquid chromatography electrospray ionization tandem mass spectrometry LMWC: Low molecular weight complex Mn: Manganese MALDI-TOF: Matrix-assisted laser desorption/ionization MATE: Multi-antimicrobial extrusion protein MTs: Metallothioneins Mo: Molybdenum MTP1: Metal transport protein Nramp: Natural resistance-associated macrophage proteins Pb: Lead PC: Phytochelatin PCR: Polymerase chain reaction PCS: Phytochelatin synthase ROS: Reactive oxygen species rp-LC: Reverse phase liquid chromatography Zn: Zinc ZIP: Zrt-Irt-like proteins References Ahmad J, Ali AA, Baig MA (2019) Role of phytochelatins in cadmium stress tolerance in plants

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TABLE 2 Clinical summary of indirect antioxidant intervention in ASD