Hyperglycemia increases the production of Amyloid Beta-peptide leading to decreased endothelial tight junction
(2022, May 13)
It belongs to a group of medications called GLP-1 receptor agonists, which help your body feel fuller for longer, reduce hunger, and stabilize blood sugar levels
Gao L, Lee BW, Chawla M et al (2023) Tirzepatide versus insulin glargine as second-line or third-line therapy in type 2 diabetes in the Asia-Pacific region: the SURPASS-AP-Combo trial
Your weight If you are obese and have a higher body mass index, you may need tirzepatide treatment for a longer time and at higher doses (if your body tolerates it) compared to those with a lower body mass index or those who are a bit overweight
These include: Blood glucose readings above your target range, especially if over 300 mg/dL Increased thirst and urination Unexplained fatigue or weakness Fruity-smelling breath Nausea or vomiting (which may indicate hyperglycemia rather than medication side effects) Seek urgent care if your blood glucose is above 300 mg/dL or above 250 mg/dL with moderate to large ketones, if you have persistent vomiting, inability to keep fluids down, confusion, or signs of dehydration