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B12 and iron supplements can help with energy deficiencies if appetite is reduced

Action plan: Try alternative fluid sources

heterogeneity was considered low, moderate, substantial, or considerable for estimated I 2 value of 040%, 3060%, 5090%, and 75100%, respectively

Common modifications include staying at a dose for 8 weeks instead of 4, adding intermediate steps like 0.375 mg or 0.75 mg, or dropping back a tier if gastrointestinal side effects become severe

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