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Also known as glucagon-like peptide-1 receptor agonists, the GLP-1 drug class includes prescription medications that are used to treat type 2 diabetes mellitus (T2DM) and obesity

Phase 2 data showed up to 24.2% body weight reduction at the highest dose over 48 weeks

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Design of the TRIUMPH Phase 3 program

Apply a thin layer to the most sensitive areas

Individual variation in GLP-1 receptor expression and gastrointestinal motility explains why one person tolerates a dose easily while another experiences significant symptoms at the same level