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PMID 36109647

Unlike many weight-loss products that rely on caffeine or synthetic stimulants to create quick but temporary energy boosts, ColonBroom avoids ingredients that cause jitters or late-day crashes

In some subgroups, mood outcomes actually improved alongside metabolic improvements, though researchers noted this may be driven by the physical health changes rather than a direct neurological effect of semaglutide

Wu Z, Chen L, Guo W, Wang J, Ni H, Liu J, Jiang W, Shen J, Mao C, Zhou M, Wan M

Participants who faced access issues reported a 13.7% weight loss within 12 months and a 14.9% loss within 24 months, on average

Ultrastructural changes in enterocytes in subjects with Hashimotos thyroiditis