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Thus, it is highly significant that cytosolic GPX1 has been shown to interact with an inactive C145A mutant of M pro , the main cysteine protease of SARS-CoV-2, but not with catalytically active wild-type M pro

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However, when the intestinal barrier is compromised (often referred to as leaky gut), this critical function is disrupted

Increased BBB permeability enhances activation of microglia and exacerbates loss of dendritic spines after transient global cerebral ischemia

Diclofenac was administered for 7 days