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This is a misconception

Use within 36 months

A comprehensive biomarker panel often includes markers of mitochondrial function, iron metabolism, and neuroinflammation

Current research implicates several interrelated pathogenic mechanisms, including persistent neuroinflammation, mitochondrial dysfunction [27], excessive production of reactive oxygen species (ROS) [28], reduced dopamine synthesis [8], impaired cerebral glucose metabolism [8], and the accumulation of misfolded -synuclein in the form of Lewy bodies [29]

It's just less invasive, less daunting

The supernatant was then analyzed by HPLC with a Rainin Econosphere ODS C18 column and an acetonitrile/water mobile phase containing 0.1% trifluoroacetic acid